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10.1016/j.theriogenology.2022.10.005 17 DaiZ.WuZ.HangS.ZhuW.WuG
Specifically, researchers examined the effects of intra-articular injections of AOD9604, both alone and in combination with HA, on cartilage morphology, histopathology, and functional outcomes such as lameness
Liver enzyme elevations (ALT and AST above 3 times the upper limit of normal) occurred at rates similar between orforglipron and placebo groups, with no dose-dependent pattern suggesting drug-related hepatotoxicity
it is produced by traditional organic synthesis and supplied as a crystalline solid for laboratory reconstitution in a research-appropriate solvent
These include water retention, joint discomfort, or changes in blood sugar regulation
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